CONFERENCE ABSTRACTS

2018
iPSC-derived neuronal/astrocyte composite cultures identify functional and bioenergetic defects in Leigh syndrome patients carrying SURF1 mutations. 2-7 November 2018, San Diego, CA, USA. Session 185.07.

Modeling Huntington’s disease (HD) by Cas9-based gene editing in isogenic patient-specific induced pluripotent stem cells (hiPSCs). 2-7 November 2018, San Diego, CA, USA. Session 518.08/JJJ4.

2017
Lisowski P, Mlody B, Kannan P, Priller J, Wanker E, Kühn R, Prigione A. Inactivation of neurotoxic CAG expansion repeats in patient iPSC-derived neurons using highly specific Cas9 gene editing system. 47th Annual Meeting of the Society for Neuroscience, 11-15 November 2017, Washington DC, USA.

Golonko A, Ploski R, Lisowski P. Huntington’s Disease HTT gene editing, clonal isolation and differentiation into neurons of interest of patient-specific induced pluripotent stem cells (hiPSCs) using high fidelity Cas9 system. EUROBIOTECH. 6th Central European Congress of Life Sciences. 11th-14th September 2017, Krakow, Poland.

Golonko A, Pollak A, Rydzanicz M, Ploski R, Lisowski P. Human induced pluripotent stem cell (hiPSCs) based Huntington’s Disease (HD) neurons and their genetic correction using personalized RNA-guided designer nucleases (Cas9) mediated genome editing. Polish Neuroscience Society 13th International Congres, 28-31 August, Warsaw, Poland.

Zink A, Inak G, Lisowski P, Priller J, Prigione A. Estabilishmet of a human stem cell-based model of alcohol use disorders. Stem Cell Network North Rhine Westphalia International Meeting, 16-17 May 2017, Münster, Germany.

Kannan P, Mlody B, Lisowski P, Priller J, Wanker E, Prigione A. Assesing the impact of mutant huntingtin on neuronal mitochondrial functions using patient derived iPCs. Stem Cell Network North Rhine Westphalia International Meeting, 16-17 May 2017, Münster, Germany.

2016
Golonko A, Lisowski P. Gene therapy of Huntington’s disease – inactivation of neurotoxic CAG expansion repeats using personalized and highly specific gene editing system. Ogólnopolska Neurobiologiczna Konferencja Naukowa „Neuron”. 2 – 3 grudnia 2016. Lublin, Wydział Biologii i Biotechnologii UMCS, Polska

Lisowski P, Zhang S, Deng T, Furusawa T, Bustin M. HMGNs affect alternative isoform regulation of mRNA in prefrontal cortex, hippocampus and embryonic stem cells. 46th Annual Meeting of the Society for Neuroscience, November 12-16, 2016, San Diego, CA, USA

Grzybek M, Ploski R, Flisikowski K, Gasperowicz P, Emes R, Giles T, Wolf E, Schnieke A, Lisowski P. DNA methylation profiling of adipose mesenchymal stem cells (AMSCs) using reduced representation bisulfite sequencing (RRBS) towards efficient neurodegenerative disease modeling. 46th Annual Meeting of the Society for Neuroscience, November 12-16, 2016, San Diego, CA, USA

Grzybek M, Ploski R, Flisikowski K, Gasperowicz P, Emes R, Giles T, Wolf E, Schnieke A, Lisowski P. DNA methylation profiling of swine stem cells (AMSCs) using reduced representation bisulfite sequencing (RRBS) towards cell based disease modeling. Polski Kongres Genetyki 2016, Lodz, Poland.

Gruba K, Lisowski P. Towards idetification of new factors involved in neuronal RNA alternative isoform regulation. Polski Kongres Genetyki 2016, Lodz, Poland.

Golonko A, Lisowski P. Znaczenie metylacji DNA w patogenezie otepienia z cechami neurodegeneracji (DNA methylation in cognitive impairment with neurodegenerations). Liczby – Komputery – Zycie 2016, Krakow, Poland.

Gruba K, Lisowski P. Alternative splicing on computer screen. Liczby – Komputery – Zycie 2016, Krakow, Poland

2014
Lisowski P, Zhang S, Deng T, Furusawa T, Bustin M. RNA-sequencing implicates HMGN1 and HMGN2 in the modulation of transcriptional profiles of prefrontal cortex and hippocampus in mice. 44th Annual Meeting of the Society for Neuroscience, November 15-19, 2014, Washington, DC, USA

Lisowski P, Stankiewicz AM, Piotrowski A, Ronowicz A, Juszczak GR, Swiergiel AH. Repeated social stress affects DNA methylation of genes associated with CRH/UCN3, arginine-vasopressin and renin-angiotensin systems in adult mouse hippocampus. 44th Annual Meeting of the Society for Neuroscience, November 15-19, 2014, Washington, DC, USA

Stankiewicz AM, Goscik J, Lisowski P, Majewska A, Swiergiel AH, Juszczak GR. Repeated social stress affects expression of hemoglobin genes in mouse prefrontal cortex. 44th Annual Meeting of the Society for Neuroscience, November 15-19, 2014, Washington, DC, USA

Szmidt M, Stankiewicz AM, Lisowski P, Sokolowska J, Sysa P, Urbanska K. The influence of silver nanoparticles (AgNPs) on the expression of proliferation and apoptosis-related genes of glioblastoma multiforme (GBM) cells cultured on in ovo model. 9th International Conference of Anticancer Research, October 6-10, 2014, Porto Carras, Sithonia, Greece

2013
Lisowski P, Stankiewicz AM, Ronowicz A, Piotrowski A, Juszczak GR, Wieczorek M, Swiergiel AH. Repressive epigenetic changes at the promoters of 5-HT3B, 5-HT1F, and 5-HT7 receptors in the hippocampus of mice subjected to chronic social stress. 43th Annual Meeting of the Society for Neuroscience, November 9-13, 2013, San Diego, California, USA

Lisowski P, Stankiewicz AM, Goscik J, Wieczorek M, Swiergiel AH, Dyr W, Ryglewicz D, Stefanski R. Transcriptome analysis of frontal cortex, hippocampus and nucleus accumbens in alcohol-preferring and nonpreferring rats. 11thInternational Congress of Polish Neuroscience Society, September 15-17, 2013, Poznan, Poland

Stankiewicz AM, Goscik J, Juszczak GR, Majewska A, Swiergiel AH, Lisowski P. Dynamic changes in mouse hippocampal gene expression during chronic stress. 11th International Congress of Polish Neuroscience Society, September 15-17, 2013, Poznan, Poland

Stankiewicz AM, Swiergiel AH, Juszczak GR, Goscik J, Majewska A, Lisowski P. Dynamics of gene expression patterns in frontal cortex and hippocampus of mice subjected to chronic social stress. 43th Annual Meeting of the Society for Neuroscience, November 9-13, 2013, San Diego, California, USA

Wieczorek M, Stankiewicz AM, Goscik J, Stefanski R, Dyr W, Ryglewicz D, Swiergiel AH, Lisowski P. Limbic system transcriptome profiling in alcohol-preferring and nonpreferring rats. 43th Annual Meeting of the Society for Neuroscience, November 9-13, 2013, San Diego, California, USA

Golas A, Lisowski P, Kotarska K, Zwierzchowski L, Styrna J. Deletion on Y chromosome influences the sperm DNA methylation patterns in mice. IV Polski Kongres Genetyki, September 10-13, 2013, Poznan, Polska

2012
Lisowski P, Stankiewicz AM, Ronowicz A, Piotrowski A, Juszczak GR, Goscik J, Zwierzchowski L, Swiergiel AH. Genome-wide DNA methylation profiling in hippocampus of mice subjected to chronic social stress. 42th Annual Meeting of the Society for Neuroscience, October 13-17, 2012, New Orleans, Louisiana, USA: 898.16/TT17.

Stankiewicz AM, Goscik J, Juszczak GR, Wieczorek M, Swiergiel AH, Lisowski P. Stress responsiveness-specific phenotype associated with different hippocampal transcritome downregulation during chronic tricyclic antidepressant treatment. 8th FENS Forum of Neuroscience, July 14-18, 2012, Barcelona, Spain: 3689. Citation: FENS Abstract, Volume 6, p127.35, 2012.

Mroz RM, Lisowski P, Minarowski L, Bierla J, Tycinska A, Sobkowicz B, Chyczewska E, Musial W, MacNee W. Antiinflammatory effects of add-on atorvastatin therapy during the treatment of COPD patients. American Thoracic Society International Conference, May 18-23, 2012, San Francisco, California, USA: 30907. Citation: American Journal of Respiratory and Critical Care Medicine Vol 185. pp. A2265, (2012).

2011
Lisowski P, Stankiewicz MA, Goscik J, Juszczak GR, Zwierzchowski L, Swiergiel AH. Microarray datasets reveal common gene signature of chronic stress response and antidepressant action in mouse brain. 4th International Symposium on Animal Functional Genomics, October 10-12, 2011, Dublin, Ireland. Abstract P100, page 32.

SYMPOSIUM 325: Neural and Molecular Mechanisms of Stress: Swiergiel AH, Stankiewicz A, Juszczak G, Wieczorek M, Lisowski P. Hippocampal transcriptome associated with stress-induced analgesia phenotype in mice – involvement of genes coding receptors for neurotensin (Ntsr2) and GABA (Gabard). 41th Annual Meeting of the Society for Neuroscience, November 12-16, 2011, Washington, DC, USA: 325.09.

Lisowski P, Stankiewicz A, Juszczak GR, Swiergiel AH. Repeated but not acute social stress upregulate hippocampal transcription of genes implicated in demetia and anxiety in mice. 41th Annual Meeting of the Society for Neuroscience, November 12-16, 2011, Washington, DC, USA: 821.01/VV29.

Stankiewicz A, Zabielska J, Milewczyk A, Korowin M, Gasiorkiewicz I, Swiergiel AH, Juszczak GR, Lisowski P. Effect of acute and repeated social stress on hippocampal transcriptome in mice. 10th International Congress of Polish Neuroscience Society, September 21-24, 2011, Lodz, Poland, Poster P5.10. Citation: Acta Neurobiologiae Experimentalis Vol 71: 58-59.

Mroz RM, Tycinska A, Minarowski L, Bierla J, Lisowski P, Sobkowicz B, Chyczewska E, Musial WJ, MacNee W. Pleiotropic Effects Of Add-Onn Atorvastin Therapy During The Treatment Of COPD Patients. European Respiratory Society Annual Congress, September 24-28, 2011, Amsterdam, NL: 855281.

Lisowski P, Stankiewicz A, Juszczak GR, Wieczorek M, Swiergiel AH. Hippocampal Transcriptome Associated With Stress-Induced Analgesia Phenotype In Mice – Involvement Of Nts2 Receptors. European Opioid Conference, April 13-15, 2011, Krakow, Poland. Abstract book page 247.

Mroz RM, Tycinska A, Minarowski L, Bierla J, Lisowski P, Sobkowicz B, Chyczewska E, Musial WJ, MacNee W. Effects Of Add-On Atorvastatin Therapy During The Treatment Of COPD Patients. American Thoracic Society International Conference, May 13-18, 2011, Denver, Colorado, USA: 20640.

2010
Lisowski P, Juszczak GR., Goscik J, Zwierzchowski L, Wieczorek M, Swiergiel AH. Effects of desipramine treatment on hippocampal transcriptome in mice differing in responses to antidepressants. 23nd European College of Neuropsychopharmacology, Amsterdam, The Netherlands 2010: Paper number CG10-0702, Poster number P.1.a.021, Citation: The Journal of European College of Neuropsychopharmacology Vol 20, S3, S224

Lisowski P, Juszczak GR., Goscik J, Wieczorek M, Zwierzchowski L, Swiergiel AH. Effect of chronic stress on frontal cortex transciptome in mice. 40nd Annual Meeting of the Society for Neuroscience, November 13-17, 2010 San Diego, Calif, USA: 597.3/III14.

Klejman A, Bieganska K, Wawrzyniak M, Dabrowski M, Owczarek D, Lisowski P, Balcerzyk M, Kaczmarek L. Neuronal overexpression of ICER in transgenic rat model; the impact on seizure susceptibility and glucose metabolism. 40nd Annual Meeting of the Society for Neuroscience, November 13-17, 2010, San Diego, Calif, USA: 392.4/HHH39.

Lisowski P, Flisikowski K, Zwierzchowski L. Methylation profile of the INS-IGF2 locus in the liver of cattle. International Society for Animal Genetics, Edinburgh, Scotland 2010: P4052.

Lisowski P, Goscik J, Kosciuczuk EM, Oprzadek J, Pierzchala M, Zwierzchowski L. Liver transcriptomic profile of Holstein-Friesian and Hereford bulls. International Society for Animal Genetics, Edinburgh, Scotland 2010: P4051.

Olbromski R, Lisowski P, Zwierzchowski L. Expression of leptin and stearoyl-CoA desaturase genes in adipose tissue, liver and longissimus dorsi muscle of bulls of different breeds. International Society for Animal Genetics, Edinburgh, Scotland 2010: P4050.

2009
Lisowski P, Juszczak GR, Goscik J, Wieczorek M, Dunn AJ, Swiergiel AH. Different modulation of transcription profiles in hippocampus of mice bred for high and low stress-induced analgesia following chronic mild stress. 39th Annual Meeting of the Society for Neuroscience, Chicago, USA 2009: 469.16/EE50.

Wieczorek M, Juszczak GR, Lisowski P, Goscik J, Swiergiel AH. Effect of chronic mild stress on gene expression in raphe nuclei: Role of 5-HT (5B) and orphan Gpr88 receptors in stress adaptation. 39th Annual Meeting of the Society for Neuroscience, Chicago, USA 2009: 776.18/EE118.

Lisowski P, Juszczak GR., Goscik J, Wieczorek M, Swiergiel AH. Different modulation of transcription profiles in hypothalamus of mice bred for high and low stress-induced analgesia following chronic mild stress. 22nd European College of Neuropsychopharmacology, Istanbul, Turkey 2009: European Neuropsychopharmacology, Vol 19, S3, pS402.

Juszczak GR, Lisowski P, Wieczorek M, Goscik J, Sliwa AT, Swiergiel AH. Effect of chronic mild stress on gene expression in raphe nuclei: role of 5-HT (5B) and orphan Gpr88 receptors in stress adaptation in mice. 22nd European College of Neuropsychopharmacology, Istanbul, Turkey 2009: European Neuropsychopharmacology, Vol 19, S3, pS225.

2008

Lisowski P, Juszczak GR, Sliwa AT, Swiergiel AH. Transcriptome and biochemical pathway analysis of frontal cortex, hippocampus, hypothalamus and raphe nucleus of mice selectively bred for high and low analgesia. 38th Annual Meeting of the Society for Neuroscience, Washington, USA 2008: 270.3/HH2.

Lisowski P, Goscik J, Brym P, Zwierzchowski L. Transcriptional profiling and biochemical pathways analysis of liver from two breeds of cattle. International Society for Animal Genetics, Amsterdam, NL 2008: P2111.

Flisikowski K, Lisowski P, Schwarzenbacher H, Fries R. Annotation, polymorphism and expression analysis of the bovine INS-IGF2 locus. International Society for Animal Genetics, Amsterdam, NL 2008: P2232.

Lisowski P, Robakowska-Hyżorek D, Blitek A, Karczmarek M, Gajewska A, Zwierzchowski L, Zięcik A, Kochman K. Zastosowanie oznaczeń real-time PCR do badania ekspresji genów podjednostek gonadotropin, prolaktyny i folistatyny w przednim płacie przysadki świni w okresie przedowulacyjnym. 17th International Symposium on “Molecular and Physiological Aspects of Regulatory Processes in the Organism”, Cracow,

Blitek A, Lisowski P, Robakowska-Hyzorek D, Gajewska A, Kaczmarek MM, Counis R, Zwierzchowski L, Ziecik AJ, Kochman K. Cobalt complex with GnRH slightly stimulates the follistatin gene expression in the pig anterior pituitary only after long time incubation, in vitro. 17th International Symposium on “Molecular and Physiological Aspects of Regulatory Processes in the Organism”, Cracow, Poland 2008.

Robakowska-Hyżorek D, Blitek A, Lisowski P, Gajewska A, Kaczmarek MM, Ziecik AJ, Zwierzchowski L, Kochman K. Modulation of follistatin gene expression by Cu-GnRH complex in the pig anterior pituitary, in vitro. 17th International Symposium on “Molecular and Physiological Aspects of Regulatory Processes in the Organism”, Cracow, Poland 2008.

Lisowski P, Goscik J, Brym P, Zwierzchowski L. Zastosowanie baz danych w analizie transkryptomu bydła. Zwierzęta w badaniach naukowych, Warszawa 2008: Prace i Materiały Zootechniczne, Vol 66, s 180-182.

2007
Lisowski P, Goscik J, Zwierzchowski L. Profil ekspresji genów GHR, IGF1 i IGF2 w wątrobie bydła w trakcie rozwoju osobniczego. Polski Kongres Genetyki, Warszawa 2007: GZ12, s 211.

Lisowski P, Goscik J, Zwierzchowski L. Analiza profilu ekspresji genów GHR, IGF1 i IGF2 w wątrobie buhajków ras bydła zróżnicowanych pod względem typu użytkowania. Polski Kongres Genetyki, Warszawa 2007: GZ13, s 211-212.

2006
Lisowski P, Swiergiel AH, Tymosiak-Zielinska A, Juszczak GR, Wolak P, Sliwa AT, Sacharczuk M, Wood PB. In search for animal models of depression: Prenatal and postnatal long-term accutane treatment does not produce depression-like behavior in mice. 36th Annual Meeting of the Society for Neuroscience, Atlanta, USA 2006.